It boasts a slowly-mounting high that begins as a sense of physical relaxation and then progresses toward a state of mental fogginess. Users will feel a heavy sensation in the limbs and head and may not want to be especially active. The feeling of couchlock is commonly reported: users may have thoughts or intentions of getting up to perform a task, but will just as happily remain motionless. This immobilization can free up the mind for lazy contemplation and meandering creative thinking.

Some psychedelic effects like visual distortions and strange tactile sensations may also be present. Because of its heavy body stone, it is not recommended for active daytime use. Instead, it works well as a numbing agent for chronic pain, an anti-nausea treatment, and as a way to relieve stress and anxiety. Negative effects include dry mouth and eyes, occasionally accompanied by paranoia and dizziness. A few users have also reported experiencing anxiety from larger doses of this strain. Hundi kush is particularly helpful for users with insomnia, as large enough doses can induce sleep.